Molecular Formula | C17H27ClN4O3S2 |
Molar Mass | 435 |
Melting Point | 160 °C (decomp) |
Boling Point | 652.3°C at 760 mmHg |
Flash Point | 348.3°C |
Vapor Presure | 6.64E-18mmHg at 25°C |
Storage Condition | 2-8℃ |
introduction | furathiamine hydrochloride is white or yellowish crystalline powder, odorless or slightly similar to garlic. Slightly soluble in water or acetone; soluble in methanol, ethanol or chloroform; almost insoluble in benzene or ether. Melting point 130-136 ℃ (decomposition). |
indications | furathiamin hydrochloride is suitable for the treatment of beriberi or Wernicke encephalopathy of vitamin B1, and can also be used for the adjuvant treatment of peripheral neuritis and dyspepsia caused by vitamin B1 deficiency. |
Pharmacokinetics | Furanthiamine hydrochloride is a new derivative of vitamin B1, which is rapidly converted into active thiamine in the body. It is not decomposed by thiaminase in the body, and has strong affinity to tissues. High organ concentration, high blood concentration, long maintenance time, high efficiency, long-acting, and low toxicity. |
adverse reactions | furathiamine hydrochloride occasionally sees dizziness, fatigue, nausea and vomiting, which disappears after drug withdrawal; local injection occasionally has hard lump, which can gradually disappear after hot compress or drug withdrawal. |